Manchester United face Turkey’s Fenerbahce and Dutch side Feyenoord in the group stage of the Europa League following the draw in Monaco on Friday.
Fellow Premier League side Southampton are in a group with Inter Milan, Sparta Prague and Israel’s Hapoel Beer-Sheva.
United go into the first campaign under Jose Mourinho with one of the more difficult groups, completed by Ukraine’s Zorya.
For Fenerbahce’s Dutch striker striker Robin van Persie, it means a meeting with two former clubs in Feyenoord and United.
Group A: Manchester United, Fenerbahce, Feyenoord, Zorya
Group B: Olympiakos, Apoel Nicosia, Young Boys Bern, Astana
Group C: Anderlecht, Saint-Etienne, Mainz, Gabala
Group D: Zenit St Petersburg, AZ Alkmaar, Maccabi Tel Aviv, Dundalk
Group E: Viktoria Plzen, Roma, Austria Vienna, Astra Giurgiu
Group F: Athletic Bilbao, Genk, Rapid Vienna, Sassuolo
Group G: Ajax, Standard Liege, Celta Vigo, Panathinaikos
Group H: Shakhtar Donetsk, Braga, KAA Gent, Konyaspor
Group I: Schalke, Salzburg, Krasnodar, Nice
Group J: Fiorentina, PAOK, Slovan Liberec, Qarabag
Group K: Inter Milan, Sparta Prague, Southampton, Hapoel Beer-Sheva
Group L: Villarreal, Steaua Bucharest, Zurich, Osmanispor
The group stage begins on September 15 and runs until Decemeber 8. The final will be played in Solna, Sweden on May 24